发明名称 |
METHODS AND SYSTEMS FOR INDUCIBLE ABLATION OF NEURAL CELLS |
摘要 |
The present invention relates to methods and systems for inducible ablation of neural cells, in particular non-proliferating cells, such as oligodendrocytes and Schwann cells. The methods and systems include an animal model that can be specifically induced to display phenotypic traits or characteristics of a demyelination condition. The methods and systems disclosed herein are useful for drug screening, by identifying compounds or agents that promote remyelination or reversal of phenotypic traits or characteristics of demyelination conditions.
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申请公布号 |
CA2773109(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
CA20102773109 |
申请日期 |
2010.09.02 |
申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
POPKO, BRIAN;TRAKA, MARIA |
分类号 |
A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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