发明名称 |
REHYDRATABLE THIOLATED POLYSACCHARIDE PARTICLES AND SPONGE |
摘要 |
<p>Tissue and other body structures may be protected using a hydrated composition made from free-flowing rehydratable particles or a rehydratable sponge comprising substantially collagen-free dehydrothermally crosslinked thiolated polysaccharide. Rehydration of crosslinked or uncrosslinked polysaccharide particles may be carried out without clumping by dispersing the particles in a biocompatible water-miscible polar dispersant such as ethanol and combining the dispersion with sufficient aqueous solvent for the particles to convert them to a cohesive hydrogel. The hydrated particles or sponge may assist in returning an injured, inflamed or surgically repaired surface to a normal state, e.g., through one or more healing mechanisms such as modulation of an inflammatory response, phagocytosis, mucosal remodeling, reciliation or other full or partial restoration of normal function.</p> |
申请公布号 |
EP2291524(A2) |
申请公布日期 |
2011.03.09 |
申请号 |
EP20090735120 |
申请日期 |
2009.04.23 |
申请人 |
MEDTRONIC, INC |
发明人 |
MYNTTI, MATTHEW, F.;OLIVER, DANA, A.;VACCARO, BRIAN, J. |
分类号 |
C12N15/82 |
主分类号 |
C12N15/82 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|