发明名称 PARTICULATE COMPOSITION CONTAINING ANHYDROUS CRYSTALLINE 2-O-.ALPHA.-D-GLUCOSYL-L-ASCORBIC ACID, PROCESS FOR PRODUCING THE SAME, AND USES THEREOF
摘要 The present invention aims to provide a particulate composition containing anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic acid having a significantly, hardly solidifiable property compared to conventional ones in a grade for use in quasi-drugs; a process for producing the same; and uses thereof. The present invention solves the above object by providing a particulate composition containing anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic in an amount of over 98.0% by weight but less than 99.9% by weight, on a dry solid basis; or a degree of crystallinity of 90% or higher for anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic acid, when calculated based on a profile of powder X-ray diffraction analysis of the particulate composition, and a dynamic vapor sorption level of 0.01% by weight or lower, when kept at 25°C under a relative humidity of 35% by weight for 12 hours after removal water in the particulate composition under nitrogen gas stream; and by providing a process for producing the same and uses thereof.
申请公布号 CA2714377(A1) 申请公布日期 2011.03.03
申请号 CA20102714377 申请日期 2010.09.03
申请人 KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO 发明人 SHIBUYA, TAKASHI;IZAWA, SEISUKE;NISHIMOTO, TOMOYUKI;FUKUDA, SHIGEHARU;MIYAKE, TOSHIO
分类号 A61K47/26;A23L1/30;A61K9/14;A61K31/375;C07H17/04;C12P19/60 主分类号 A61K47/26
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