| 发明名称 |
NKG2D antibodies for use in the treatment of rheumatoid arthritis or Crohn's disease |
| 摘要 |
The present invention relates to methods and compositions for treating and/or preventing autoimmune and/or inflammatory disease. In particular, the present invention provides therapeutics for impairing the expansion and function of autoreactive T cells and/or NK cells, by modulating NKG2D. |
| 申请公布号 |
EP2289534(A1) |
申请公布日期 |
2011.03.02 |
| 申请号 |
EP20100183329 |
申请日期 |
2005.04.05 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LANIER, LEWIS L.;OGASAWARA, KOETSU;BLUESTONE, JEFFREY A. |
| 分类号 |
A61K39/395;A61K38/00;A61P1/00;A61P19/02;A61P37/02;C07K16/28 |
主分类号 |
A61K39/395 |
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