发明名称 |
NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE |
摘要 |
The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity. In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I): in which R means the component with non-steroidal anti inflammatory activity. In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI. The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity. |
申请公布号 |
KR20110010606(A) |
申请公布日期 |
2011.02.01 |
申请号 |
KR20107025107 |
申请日期 |
2009.04.09 |
申请人 |
EMS S.A.;UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO-UNESP |
发明人 |
VIZIOLI EDNIR DE OLIVEIRA;CHIN CHUNG MAN;MENEGON RENATO FARINA;BLAU LORENA;SANTOS JEAN LEANDRO DOS;LONGO MARIA DO CARMO |
分类号 |
C07C309/14;A61K31/10;A61P29/00;C07C303/22 |
主分类号 |
C07C309/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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