发明名称 NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE
摘要 The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity. In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I): in which R means the component with non-steroidal anti inflammatory activity. In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI. The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity.
申请公布号 KR20110010606(A) 申请公布日期 2011.02.01
申请号 KR20107025107 申请日期 2009.04.09
申请人 EMS S.A.;UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO-UNESP 发明人 VIZIOLI EDNIR DE OLIVEIRA;CHIN CHUNG MAN;MENEGON RENATO FARINA;BLAU LORENA;SANTOS JEAN LEANDRO DOS;LONGO MARIA DO CARMO
分类号 C07C309/14;A61K31/10;A61P29/00;C07C303/22 主分类号 C07C309/14
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