发明名称 |
Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent |
摘要 |
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid.
|
申请公布号 |
US7842307(B2) |
申请公布日期 |
2010.11.30 |
申请号 |
US20020214413 |
申请日期 |
2002.08.06 |
申请人 |
PURDUE PHARMA L.P. |
发明人 |
OSHLACK BENJAMIN;WRIGHT CURTIS;BREDER CHRISTOPHER |
分类号 |
A61K9/127;A61K9/16;A61K9/20;A61K9/50;A61K36/81 |
主分类号 |
A61K9/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|