| 发明名称 |
Histone deacetylase enzymes |
| 摘要 |
<p>Disclosed is a hydroxycarbamoyl compound of formula (I) or a salt, N-oxide, hydrate or solvate thereof, wherein R1 is a carboxylic acid group (-COOH), or an ester group, Y is a bond, -C(=O)-, -S(=O)2-, -C(=O)O-, -C(=O)NR3-, -C(=S)-NR3 , -C(=NH)NR3 or -S(=O),NR3- and wherein the remaining substituents are defined in the specification. Also disclosed is a composition comprising said compound and the use of said compound for the preparation of a composition for the treatment of for example cancer.</p> |
| 申请公布号 |
NZ560289(A) |
申请公布日期 |
2010.11.26 |
| 申请号 |
NZ20060560289 |
申请日期 |
2006.05.04 |
| 申请人 |
CHROMA THERAPEUTICS LTD. |
发明人 |
DAVIDSON, ALAN HORNSBY;PATEL, SANJAY RATILAL;MAZZEI, FRANCESCA ANN;DAVIES, STEPHEN JOHN;DRUMMOND, ALAN HASTINGS;MOFFAT, DAVID FESTUS CHARLES;BAKER, KENNETH WILLIAM JOHN;DONALD, ALISTAIR DAVID GRAHAM |
| 分类号 |
C07D487/04;A61K31/4045;A61K31/4353;A61K31/4965;A61P35/00;C07C259/06;C07C275/24;C07C311/46;C07D207/40;C07D207/416;C07D209/42;C07D213/40;C07D217/02;C07D217/12;C07D217/22;C07D295/18;C07D295/185;C07D333/62;C07D333/70;C07D471/04 |
主分类号 |
C07D487/04 |
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