发明名称 |
Nitric oxide-releasing polymers |
摘要 |
This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
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申请公布号 |
US7829553(B2) |
申请公布日期 |
2010.11.09 |
申请号 |
US20050588718 |
申请日期 |
2005.01.06 |
申请人 |
AMULET PHARMACEUTICALS, INC. |
发明人 |
ARNOLD ERNST V.;DOLETSKI BLAINE G.;RAULLI ROBERT E. |
分类号 |
A61K31/655;C07C245/04 |
主分类号 |
A61K31/655 |
代理机构 |
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代理人 |
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地址 |
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