| 发明名称 |
Human monoclonal antibodies to prostate specific membrance antigen (PSMA) |
| 摘要 |
Provided is an anti-PSMA antibody with specified CDR1, CDR2 and CDR3 sequences on light and heavy chains, conjugated to a specified tumor toxin. The immunoconjugate stimulates antibody dependent cell-mediated cytotoxicity of tumor cells and is useful for treatment of various cancers.
|
| 申请公布号 |
NZ556661(A) |
申请公布日期 |
2010.10.29 |
| 申请号 |
NZ20060556661 |
申请日期 |
2006.02.17 |
| 申请人 |
MEDAREX, INC. |
发明人 |
HUANG, HAICHUN;KING, DAVID JOHN;PAN, CHIN;CARDARELLI, JOSEPHINE M |
| 分类号 |
C07K16/28;A61P13/08 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
