Methylxanthine compounds and steroids to treat chronic respiratory diseases

摘要

Disclosed is the use of a methylxanthine compound and a steroid in the manufacture of a medicament for the treatment of a chronic respiratory disease selected from the group consisting of chronic obstructive pulmonary disease and severe asthma, wherein the methylxanthine compound is selected from theophylline, aminophylline and oxitriphylline and the steroid is a corticosteroid and the methylxanthine compound is to be administered at a dose which achieves plasma levels that are lower than 5 mglL.