发明名称 |
TARGETED SUSTAINED-RELEASE MICROSPHERE OF VASCULAR OCCLUSIVE AGENT CONTAINING SODIUM ALGINATE AND SORAFENIB, PRODUCTION METHOD AND USE THEREOF |
摘要 |
A targeted sustained-release microsphere of vascular occlusive agent, the production method and the use thereof are disclosed. Said microsphere comprises sodium alginate as the carrier and sorafenib as the targeted anti-tumor medicine and sorafenib is covered by sodium alginate. The weight ratio of sorafenib to sodium alginate is 1:1-1:30. Said microsphere is used for preparing the medicine for the treatment of solid tumor and high medicine concentration in the target regions with reduced dosage and hypotoxicity.
|
申请公布号 |
CA2758820(A1) |
申请公布日期 |
2010.10.21 |
申请号 |
CA20102758820 |
申请日期 |
2010.04.14 |
申请人 |
BEIJING SHENGYIYAO SCIENCE & TECHNOLOGY DEVELOPMENT CO., LTD |
发明人 |
LI, XINJIAN;HONG, HONG;LU, GE |
分类号 |
A61K9/50;A61K9/16;A61K31/44;A61K47/36;A61P35/00 |
主分类号 |
A61K9/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|