发明名称 |
DERIVATIVES OF [1, 3] OXAZIN- 2-ONE USEFUL FOR THE TREATMENT OF METABOLIC DISEASES SUCH AS LIPID DISORDERS |
摘要 |
This invention relates to novel compounds of an 11 ß-HSD1 inhibitor disclosed herein, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11/3-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell. |
申请公布号 |
WO2010091067(A3) |
申请公布日期 |
2010.10.07 |
申请号 |
WO2010US23021 |
申请日期 |
2010.02.03 |
申请人 |
VITAE PHARMACEUTICALS, INC.;CLAREMON, DAVID, A. |
发明人 |
CLAREMON, DAVID, A. |
分类号 |
C07D471/04;A61K31/437;A61K31/4985;A61P3/00;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|