发明名称 Nitrated heterocyclic compounds as endothelin receptor antagonist
摘要 Disclosed is a nitrosated pharmaceutical compound of general formula (I) or a pharmaceutically acceptable salt or stereoisomer thereof wherein m, m' and m'' are equal to 0 or 1, n, n' and n'' are equal to 0 or 1, s, s' and s'' are equal to 0 or 1, provided that at least one of s, s' and s'' is 1 and A is selected from the group consisting of substituents as defined in the specification. Also disclosed in the use of said compound in preparing a drug for the treatment of for example, renal diseases, a composition comprising said compound and a kit comprising said compound.
申请公布号 NZ571820(A) 申请公布日期 2010.09.30
申请号 NZ20070571820 申请日期 2007.05.23
申请人 NICOX, S.A. 发明人 ONGINI, ENNIO;ALMIRANTE, NICOLETTA;BIONDI, STEFANO
分类号 C07D209/20;A61K31/40;A61K31/41;A61K31/435;C07D239/34;C07D239/52;C07D239/60;C07D261/14;C07D401/12;C07D401/14;C07D403/12;C07D405/04;C07D405/06;C07D413/12;C07D417/04 主分类号 C07D209/20
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