NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF
摘要
A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11²-hydroxysteroid dehydrogenase type 1 (11²HSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.
申请公布号
EP1615698(B1)
申请公布日期
2010.09.29
申请号
EP20040725891
申请日期
2004.04.06
申请人
HIGH POINT PHARMACEUTICALS, LLC
发明人
ANDERSEN, HENRIK, SUNE;KAMPEN, GITA, CAMILLA, TEJLGAARD;CHRISTENSEN, INGE THOGER;MOGENSEN, JOHN, PATRICK;LARSEN, ANNETTE ROSENDAL;KILBURN, JOHN PAUL