| 发明名称 |
Pharmaceutical Compositions for the Treatment of TNF-Alpha Related Disorders |
| 摘要 |
The invention relates to a pharmaceutical composition comprising a variant TNF-α protein that inhibits the activity of soluble TNF-α while substantially maintaining the activity of transmembrane TNF-α, a buffer, and a tonicity agent, wherein said composition has a pH from approximately 5.0 to 8.0.
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| 申请公布号 |
US2010222272(A1) |
申请公布日期 |
2010.09.02 |
| 申请号 |
US20100693225 |
申请日期 |
2010.01.25 |
| 申请人 |
XENCOR, INC. |
发明人 |
DESJARLAIS JOHN R.;STEED PAUL MICHAEL;ZALEVSKY JONATHAN;SZYMKOWSKI DAVID EDMUND;CARMICHAEL DAVID F. |
| 分类号 |
A61K38/19;A61P29/00;A61P31/04;A61P37/02 |
主分类号 |
A61K38/19 |
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