Disclosed is a pharmaceutical product which is capable of exhibiting an excellent proteasome inhibitory activity, while being free from side effects such as bone marrow suppression. Specifically disclosed is a pharmaceutical composition which contains a proteasome inhibitor as an active ingredient. The proteasome inhibitor is contained in a polymeric micelle that is formed from a block copolymer having a hydrophilic segment and a hydrophobic segment.
申请公布号
WO2010098265(A1)
申请公布日期
2010.09.02
申请号
WO2010JP52556
申请日期
2010.02.19
申请人
THE UNIVERSITY OF TOKYO;KATAOKA, KAZUNORI;CABRAL, HORACIO;NISHIYAMA, NOBUHIRO;MATSUMOTO, YOKO;NAKAGAWA, SHUNSUKE;MIYAMOTO, YUICHIRO