发明名称 |
Amphiphilic macrocyclic derivatives and their analogues |
摘要 |
Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilization and/or stabilization of various compounds. Embodiments of the present invention utilize macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.
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申请公布号 |
US7786095(B2) |
申请公布日期 |
2010.08.31 |
申请号 |
US20050295724 |
申请日期 |
2005.12.07 |
申请人 |
UNIVERSITY COLLEGE DUBLIN |
发明人 |
DARCY RAPHAEL;PENKLER LAWRENCE JOHN;RAVOO BART JAN |
分类号 |
A61K31/724;C07H3/06;A61K9/48;A61K9/51;A61K47/36;A61K47/40;A61K47/48;C08B37/16 |
主分类号 |
A61K31/724 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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