The present invention relates generally to the field of sex determination of animals. Provided are methods and agents to manipulate sex determination, particularly in avian animals such as chickens, through a male chromosome-linked testis (sex) regulatory gene. Expression or activity of the DMRT1 gene or protein is modulated to produce animals with displaying a phenotype sex that differs from their genotype.
申请公布号
CA2751596(A1)
申请公布日期
2010.08.12
申请号
CA20102751596
申请日期
2010.02.08
申请人
THE UNIVERSITY OF MELBOURNE;MURDOCH CHILDRENS RESEARCH INSTITUTE
发明人
SINCLAIR, ANDREW;SMITH, CRAIG;DORAN, TIMOTHY JAMES;LOWENTHAL, JOHN WILLIAM;MOORE, ROBERT JOHN
