发明名称 Hsp90 family protein inhibitors
摘要 The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; R1 represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONR7R8 or the like; R2 represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; R3 and R5, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and R4 and R6, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.
申请公布号 US7767693(B2) 申请公布日期 2010.08.03
申请号 US20090427847 申请日期 2009.04.22
申请人 KYOWA HAKKO KIRIN CO., LTD. 发明人 NARA SHINJI;NAKAGAWA HIROSHI;KANDA YUTAKA;NAKASHIMA TAKAYUKI;SOGA SHIRO;KAJITA JIRO;SAITO JUN-ICHI;SHIOTSU YUKIMASA;AKINAGA SHIRO
分类号 A01N43/40;A61K31/12;A61K31/165;A61K31/216;A61K31/40;A61K31/4406;A61K31/4409;A61K31/445;A61K31/451;A61K31/495;A61K31/506;A61K31/5375;A61K31/5377;A61P35/00;A61P43/00;C07C49/303;C07C49/84;C07C69/738;C07C205/45;C07C235/78;C07D211/22;C07D213/40;C07D295/092;C07D295/185 主分类号 A01N43/40
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