发明名称 |
OIL-IN-WATER EMULSION INFLUENZA VACCINE |
摘要 |
The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15μg HA or a low amount such as less than 15μg HA.
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申请公布号 |
US2010189741(A1) |
申请公布日期 |
2010.07.29 |
申请号 |
US20080596202 |
申请日期 |
2008.04.16 |
申请人 |
BALLOU WILLIAM RIPLEY;HANON EMMANUEL JULES |
发明人 |
BALLOU WILLIAM RIPLEY;HANON EMMANUEL JULES |
分类号 |
A61K39/295;A61K39/145;A61P31/16 |
主分类号 |
A61K39/295 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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