发明名称 Mixed solvate of olanzapine, method for preparing it and method for preparing form I of olanzapine therefrom
摘要 Said mixed solvate is a solvate of olanzapine/water/tetrahydrofuran in the proportion 1:1:1/2 (I). The method for preparing said solvate comprises treating a crude anhydrous olanzapine with a mixture of tetrahydrofuran/water. The method for preparing Form I of olanzapine includes desolvating the mixed solvate of formula I, by means of drying, in vacuo and under temperature-controlled conditions.
申请公布号 US7759484(B2) 申请公布日期 2010.07.20
申请号 US20060568021 申请日期 2006.10.17
申请人 INKE, S.A. 发明人 DALMASES BARJOAN PERE;BESSA BELLMUNT JORDI
分类号 C07D495/04 主分类号 C07D495/04
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