A nanoparticle having one or more phosphonates or phosphinate ligands on their surface can be converted into nanoparticles with sulfonate ligands on their surface, by contacting the phosphonate-containing nanoparticles with a silylsulfonate reagent. Such nanoparticles are activated toward reactions with nucleophilic groups; thus the method provides activated nanoparticles, and methods of making and using them to produce modified nanoparticles.
申请公布号
WO2010040111(A3)
申请公布日期
2010.07.15
申请号
WO2009US59456
申请日期
2009.10.02
申请人
LIFE TECHNOLOGIES CORPORATION;TULSKY, ERIC;WELCH, ERIC;BRANCHAUD, BRUCE;MAURO, JOHN;NAASANI, IMAD