发明名称 Composition comprising an active agent with low aqueous solubility
摘要 The present invention relates to a composition comprising at least one active ingredient with low aqueous solubility, said active ingredient being present therein in a form noncovalently associated with nanoparticles formed by at least one POM polymer of formula (I), and in which said active ingredient is present in a proportion of at least 5 μmol/g of POM. It is also directed towards the use of such nanoparticles, noncovalently associated with an active ingredient, with a view to increasing the aqueous solubilization of said active ingredient.
申请公布号 US2010178337(A1) 申请公布日期 2010.07.15
申请号 US20090641773 申请日期 2009.12.18
申请人 FLAMEL TECHNOLOGIES 发明人 MEYRUEIX REMI;JORDA RAFAEL;POULIQUEN GAUTHIER;CHAN YOU-PING;BREYNE OLIVIER
分类号 A61K9/52;A61K9/14;A61K9/22;A61K31/337;A61K31/366;A61K31/403;A61K31/4418;A61K31/496;A61K38/13;A61P3/06;A61P9/12;A61P31/10;A61P35/00;A61P37/00 主分类号 A61K9/52
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