STABLE PERFLUOROCARBON EMULSION FOR USE AS AN ARTIFICIAL OXYGEN CARRIER
摘要
Perfluorocarbon emulsions having a high stability and good oxygen release are disclosed and described. These perfluorocarbon emulsions are typically for use as artificial oxygen carriers. The perfluorocarbon emulsions include a disperse phase of a perfluorocarbon and an emulsion stabilizer, and continuous phase. The emulsion stabilizer can primarily include a poly(ethylene oxide) block copolymer. These stabilized perfluorocarbon emulsions can be used in liquid and/or hydrogel phases of perfusion bioreactors or various other culture systems to enhance cell viability in thick tissue constructs, or as blood substitutes, although other applications may also be considered.
申请公布号
WO2010077671(A2)
申请公布日期
2010.07.08
申请号
WO2009US67179
申请日期
2009.12.08
申请人
UNIVERSITY OF UTAH RESEARCH FOUNDATION;RAPOPORT, NATALYA, Y.;PRESTWICH, GLENN, D.;CONDIE, RUSSELL, MORRIS