发明名称 |
PROCESS FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE AND ITS USE FOR THE PRODUCTION OF CITALOPRAM |
摘要 |
There is described a process for the preparation of 5-carboxyphthalide, which comprises adding terephthalic acid to fuming sulfuric acid containing at least 20% by weight of SO3, then adding formaldehyde to the mixture, heating the mixture at a temperature of 120-145 ~C and isolating 5-carboxyphthalide from the reaction mixture.
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申请公布号 |
CA2397497(C) |
申请公布日期 |
2010.07.06 |
申请号 |
CA20012397497 |
申请日期 |
2001.01.17 |
申请人 |
INFOSINT SA |
发明人 |
DALL'ASTA, LEONE;CASAZZA, UMBERTO;COTTICELLI, GIOVANNI |
分类号 |
C07D307/88;A61P25/24;C07D;C07D307/87 |
主分类号 |
C07D307/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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