发明名称 |
Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release |
摘要 |
The medical articles which including the following: (a) a ceramic or metallic region whose surface includes a plurality of depressions, (b) a multilayer coating region including multiple polyelectrolyte layers deposited over the surface of the ceramic or metallic region; and (c) a therapeutic agent disposed beneath or within the multilayer coating region. According to another aspect of the present invention, medical articles are provided, which include: (a) a ceramic or metallic region, (b) a multilayer coating region including multiple polyelectrolyte layers deposited over a surface of the ceramic or metallic region, the multilayer coating region including a plurality of protuberances; and (c) a therapeutic agent disposed within regions beneath the protuberances. Also described herein are methods of making such medical articles, and methods of administering a therapeutic agent to a patent using such medical articles.
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申请公布号 |
US7744644(B2) |
申请公布日期 |
2010.06.29 |
申请号 |
US20040805576 |
申请日期 |
2004.03.19 |
申请人 |
BOSTON SCIENTIFIC SCIMED, INC. |
发明人 |
WEBER JAN;NEUENDORF RACHEL |
分类号 |
A61F2/06;A61F2/00;A61F2/02;A61L31/10;A61L31/16 |
主分类号 |
A61F2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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