发明名称 |
Polyketides and antibiotics produced by combinatorial techniques |
摘要 |
Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
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申请公布号 |
US7741456(B2) |
申请公布日期 |
2010.06.22 |
申请号 |
US20060543267 |
申请日期 |
2006.10.02 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
KHOSLA CHAITAN;KAO CAMILLA M. |
分类号 |
C07H17/08;C07B61/00;C07D309/36;C07D311/92;C07D313/04;C07D323/00;C07D407/06;C12N1/21;C12N9/00;C12N15/52;C12P7/26;C12P17/06;C12P17/08;C12P17/16 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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