发明名称 |
Method for evaluation of compound using RSK1 |
摘要 |
A method for evaluation of a compound comprising the steps of introducing an RSK1 gene into a cell to prepare a cell capable of expressing RSK1, contacting a compound to be evaluated with the cell, and detecting the specific binding of the compound to RSK1; and a compound given by the method. The compound can be used as a potentiator of cisplatin. The method enables to find a gene which acts specifically on a cell of cancer induced by the abnormality in p53 or enhanced MAPK pathway and to evaluate a compound by using the gene.
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申请公布号 |
US2010151050(A1) |
申请公布日期 |
2010.06.17 |
申请号 |
US20060921621 |
申请日期 |
2006.06.06 |
申请人 |
MIZUARAI SHINJI;KOTANI HIDEHITO;SHIMOMURA TOSHIYASU;TANIGUCHI ERI |
发明人 |
MIZUARAI SHINJI;KOTANI HIDEHITO;SHIMOMURA TOSHIYASU;TANIGUCHI ERI |
分类号 |
A61K33/24;C12Q1/68 |
主分类号 |
A61K33/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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