发明名称 METHOD OF PREVENTING PULMONARY HYPERTENSION CRISES AFTER CORRECTION OF CONGENITAL HEART DISEASES IN CHILDREN
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to cardio-vascular surgery and anesthesiology in pediatrics and can be used in operative interventions caused by correction of congenital heart diseases in children. For this purpose 30 minutes before operation beginning 0.375% solution of ropivacaine is introduced into epidural cavity in amount 1 mg/kg. During operation infusion of 0.2% ropivocaine solution is carried out at rate 0.2-0.3 ml/kg/hour. In post-operational period constant infusion of 0.2% ropivocaine solution is continued at rate 0.1-0.2 ml/kg/hour during 2 days. ^ EFFECT: method allows to prevent expressed increase of pulmonary-arterial pressure in response to any stimuli due to post-ganglionic sympathetic blockade preventing activation of simpathico-adrenal system on tone of lesser circulation vessels. ^ 1 ex
申请公布号 RU2391096(C1) 申请公布日期 2010.06.10
申请号 RU20080148648 申请日期 2008.12.09
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BASHKIRSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" (GOU VPO BGMU ROSZDRAVA);OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU NAUCHNO-PROIZVODSTVENNOE OB"EDINENIE "BASHBIOMED" (OOO NPO "BASHBIOMED") 发明人 PLECHEV VLADIMIR VJACHESLAVOVICH;MIRONOV PETR IVANOVICH;KHABIBULLIN IL'DAR MARATOVICH;ONEGOV DMITRIJ VASIL'EVICH;NAGAEV IL'GIZ AMIROVICH;ABZALOV RUSTEHM RABISOVICH
分类号 A61K31/165;A61M19/00;A61P23/00 主分类号 A61K31/165
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