发明名称 |
COMPOSITIONS OF ASYMMETRIC INTERFERING RNA AND USES THEREOF |
摘要 |
The present invention provides asymmetrical duplex RNA molecules that are capable of effecting sequence-specific gene silencing. The RNA molecule comprises a first strand and a second strand. The first strand is longer than the second strand. The RNA molecule comprises a double-stranded region formed by the first strand and the second strand, and two ends independently selected from the group consisting of 5′-overhang, 3′-overhang, and blunt end. The RNA molecules of the present invention can be used as research tools and/or therapeutics. |
申请公布号 |
EP2193140(A2) |
申请公布日期 |
2010.06.09 |
申请号 |
EP20080828867 |
申请日期 |
2008.08.27 |
申请人 |
BOSTON BIOMEDICAL, INC. |
发明人 |
LI, CHIANG, JIA;SUN, XIANGAO;ROGOFF, HARRY;LI, YOUZHI |
分类号 |
C12N15/11 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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