| 发明名称 |
STEREOSELECTIVE REDUCTION OF A MORPHINONE |
| 摘要 |
A synthetic method is provided, wherein the method comprises stereoselectively reducing a ketone of a morphinone to form a reduced morphinone and optionally covalently attaching a water soluble polymer to the reduced morphinone. |
| 申请公布号 |
EP2010539(A4) |
申请公布日期 |
2010.06.02 |
| 申请号 |
EP20070755867 |
申请日期 |
2007.04.19 |
| 申请人 |
NEKTAR THERAPEUTICS |
发明人 |
CHENG, LIN;BENTLEY, MICHAEL D. |
| 分类号 |
A61K31/485;C07D489/02 |
主分类号 |
A61K31/485 |
| 代理机构 |
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