发明名称 |
COMPOUNDS AND METHODS FOR REDUCING THE RECRUITMENT AND/OR MIGRATION OF POLYMORPHONUCLEAR CELLS |
摘要 |
<p>A therapeutically effective amount of an oligonucleotide is capable of influencing the properties and behaviour of polymorphonuclear cells, e.g. suppressing endothelial adhesion and transmigration of said cells, and through this mechanism reduce the recruitment and/or migration of polymorphonuclear cells to a site of inflammation.</p> |
申请公布号 |
CA2778938(A1) |
申请公布日期 |
2010.05.14 |
申请号 |
CA20092778938 |
申请日期 |
2009.10.28 |
申请人 |
INDEX PHARMACEUTICALS AB |
发明人 |
ADMYRE, CHARLOTTE;AXELSSON, LARS-GORAN;VON STEIN, OLIVER;ZARGARI, AREZOU |
分类号 |
C12N15/117;A61K31/7088;A61K31/7125;A61P9/10 |
主分类号 |
C12N15/117 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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