发明名称 |
SIRTUIN MODULATING IMIDAZOTHIAZOLE COMPOUNDS. |
摘要 |
<p>Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.</p> |
申请公布号 |
MX2009013976(A) |
申请公布日期 |
2010.04.27 |
申请号 |
MX20090013976 |
申请日期 |
2008.06.20 |
申请人 |
SIRTRIS PHARMACEUTICALS, INC. |
发明人 |
BEMIS, JEAN;LUNSMANN, WALTER, JOSEPH;DISCH, JEREMY S.;JIROUSEK, MICHAEL;NG, PUI YEE;VU, CHI B. |
分类号 |
C07D513/04;A61K31/429;A61P3/10 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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