| 发明名称 |
THERAPEUTIC METHODS USING WRN BINDING MOLECULES |
| 摘要 |
The present invention provides, inter alia, compositions and methods for treating various diseases and disorders in a mammal by administering to a mammal in need an effective amount of a composition comprising a non-DNA small molecule that binds WRN, such as members of the spirooxindole (SPOX) class.
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| 申请公布号 |
US2010093716(A1) |
申请公布日期 |
2010.04.15 |
| 申请号 |
US20070438793 |
申请日期 |
2007.08.29 |
| 申请人 |
TRUSTEES OF BOSTON UNIVERSITY AND PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
GILCHREST BARBARA A.;ELLER MARK S.;KOEHLER ANGELA N.;MCPHERSON OLIVIA M.;NEUMANN CHRISTOPHER S.;LEWIS TIMOTHY A. |
| 分类号 |
A61K31/5386;A61P35/04;C07D498/20 |
主分类号 |
A61K31/5386 |
| 代理机构 |
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