ANTI-TUMOR ACTIVITY OF AECHL-I, A NOVEL TRITERPENOID ISOLATED FROM AILANTHUS EXCELSA IN VITRO AND IN VIVO.

摘要

A novel chemical moiety triterpenoid AECHL-1 isolated from root bark of Ailanthus excelsa having anti-cancer properties exhibiting remarkable activity in treatment of various forms of tumors with specificity wherein it blocks the growth of four tumor cell lines distinct origins and of different p53 status (B16F10 mouse melanoma, PC3 human prostate cancer, MCF-7 and MDA-MB-231 human breast cancer).