Integrated monolithic microfabricated dispensing nozzle and liquid chromatography-electrospray system and method.

摘要

An electrospray device comprises a capillary tube (52) having a passage for conducting fluids through the capillary tube and connecting an entrance orifice and an exit orifice (56). First and the second electrodes are positioned to define an electric field surrounding the exit orifice (56). The first electrode (70) circumscribes the capillary tube proximate the exit orifice, and the second electrode imparts a second potential to the fluid. A mass spectrometry device may be provided to receive fluid droplets/sprays of fluid (60,62) from the exit orifice (56).