发明名称 |
METHOD FOR THE IDENTIFICATION OF GENES INVOLVED IN NEURODEGENERATIVE PROCESSES |
摘要 |
A method for the identification of genes involved in neurodegenerative processes, detectable by the late onset of a phenotype associated with neurodegeneration, by means of a genetic screen of deregulated genes, which comprises the measurement of sleep-wake cycle activity schemes in different stages of life, young and adult, of individuals of an animal model, such as Drosophila. A mutant fly whose genome comprises a disruption in its enabled gene, with decrease of the enabled gene expression, and exhibiting a late onset neurodegenerative phenotype in adulthood. |
申请公布号 |
WO2010023605(A2) |
申请公布日期 |
2010.03.04 |
申请号 |
WO2009IB53681 |
申请日期 |
2009.08.20 |
申请人 |
INIS BIOTECH LLC;FUNDACION INSTITUTO LELOIR;CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS YTECNICAS (CONICET);CERIANI, MARIA, FERNANDA;REZAVAL, CAROLINA;BERNI, JIMENA |
发明人 |
CERIANI, MARIA, FERNANDA;REZAVAL, CAROLINA;BERNI, JIMENA |
分类号 |
C12N15/12;C12N15/00;C12Q1/68 |
主分类号 |
C12N15/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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