发明名称 QUINOXALINE DERIVATIVES
摘要 The invention discloses quinoxaline derivatives or salts thereof having PDE9-inhibiting activity and being useful as treating agent of dysuria and the like, which are represented by the formula (I) in the formula, R1 and R2 each independently stands for hydrogen, halogen, alkyl, alkoxy, acyl, amino and the like, R3 stands for alkyl, aryl, saturated carbocyclic group, saturated heterocyclic group, acyl and the like, R4 stands for hydrogen, hydroxy, alkyl or amino, R5 and R8 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkoxy, cyano or nitro, R6 and R7 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, cyano, amino, carbocyclic group, heterocyclic group, COR9 or SO2R9, R9 stands for hydrogen, hydroxy, alkyl, amino, pyrrolidin-1-yl, piperidin-1-yl, pyperazin-1-yl or the like, X stands for S or O, and A1, A2 and A3 each independently stands for N or C.
申请公布号 US2010048556(A1) 申请公布日期 2010.02.25
申请号 US20070448212 申请日期 2007.12.12
申请人 OKADA MAKOTO;SATO SHUICHIRO;KAWADE KENJI;GOTANDA KOTARO;SHINBO ATSUSHI;NAKANO YOUICHI;KOBAYASHI HIDEO 发明人 OKADA MAKOTO;SATO SHUICHIRO;KAWADE KENJI;GOTANDA KOTARO;SHINBO ATSUSHI;NAKANO YOUICHI;KOBAYASHI HIDEO
分类号 A61K31/5377;A61K31/5025;A61P9/10;A61P13/10;A61P13/12;C07D413/02;C07D471/04 主分类号 A61K31/5377
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