发明名称 |
PIM KINASE INHIBITORS AND METHODS OF THEIR USE |
摘要 |
New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase- mediated disorder, such as cancer.
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申请公布号 |
KR20100015331(A) |
申请公布日期 |
2010.02.12 |
申请号 |
KR20097020450 |
申请日期 |
2008.03.03 |
申请人 |
NOVARTIS AG |
发明人 |
BURGER MATTHEW;LINDVALL MIKA;HAN, WOO SEOK;LAN JIONG;NISHIGUCHI GISELE;SHAFER CYNTHIA;BELLAMACINA CORNELIA;HUH KAY;ATALLAH GORDANA;MCBRIDE CHRISTOPHER;ANTONIOS MCCREA WILLIAM JR.;ZAVOROTINSKAYA TATIANA;WALTER ANNETTE;GARCIA PABLO |
分类号 |
C07D401/12;A61K31/44;A61P35/00;C07D213/78 |
主分类号 |
C07D401/12 |
代理机构 |
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