摘要 |
The invention generally relates to topical and aerosolized compositions for inducing vasoconstriction with low incidence of rebound hyperemia The compositions comprise highly selective alpha-2 adrenergic receptor agonists, at low concentrations, such as below 0.05% weight by volume The compositions preferably comprise brimonidine The compositions preferably have pH between about 5.5 and about 6.5. |