COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES TO NUCLEIC ACIDS
摘要
The present invention is directed to methods and compositions for modulating an immune response generated by a subject in response to the administration of a nucleic acid. The invention includes methods and compositions for enhancing an immune response generated by the administration of an immunostimulatory oligonucleotide by coadministration of a lipid particle, as well as methods of reducing an immune response generated by the administration of a nucleic acid by coadministration of an inhibitor of a src family kinase.
申请公布号
WO2009108235(A3)
申请公布日期
2010.01.14
申请号
WO2008US85571
申请日期
2008.12.04
申请人
TEKMIRA PHARMACEUTICALS CORPORATION;UNIVERSITY OF BRITISH COLUMBIA;TAM, YING, K.;DE JONG, SUSAN, D.;WILSON, KALEY, D.
发明人
TAM, YING, K.;DE JONG, SUSAN, D.;WILSON, KALEY, D.