发明名称 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
摘要 The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein: W, A, Y, Z, R101 and R200 are described in the specification.
申请公布号 US7642270(B2) 申请公布日期 2010.01.05
申请号 US20060519611 申请日期 2006.09.12
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 PLAYER MARK R.;HUANG HUI;HUTTA DANIEL A.;DESJARLAIS RENEE L.
分类号 A61K31/44;C07D471/06 主分类号 A61K31/44
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