发明名称 N-ACYLTHIOUREA AND N-ACYLUREA INHIBITORS OF THE HEDGEHOG PROTEIN SIGNALLING PATHWAY
摘要 The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, and also to novel acylthiourea or acylurea derivatives of formula (I) as such, to their use as a medicinal product, and to pharmaceutical compositions containing them.
申请公布号 WO2009130422(A3) 申请公布日期 2009.12.30
申请号 WO2009FR00442 申请日期 2009.04.16
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;RUAT, MARTIAL;FAURE, HELENE;TRAIFFORT, ELISABETH;SCHOENFELDER, ANGELE;MANN, ANDRE;TADDEI, MAURIZIO;SOLINAS, ANTONIO;MANETTI, FABRIZIO 发明人 RUAT, MARTIAL;FAURE, HELENE;TRAIFFORT, ELISABETH;SCHOENFELDER, ANGELE;MANN, ANDRE;TADDEI, MAURIZIO;SOLINAS, ANTONIO;MANETTI, FABRIZIO
分类号 C07C335/26;A61K31/17;A61P3/10;A61P25/00;C07C275/54;C07D209/06;C07D213/81;C07D235/14;C07D307/68;C07D317/68;C07D319/18;C07D333/38 主分类号 C07C335/26
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