发明名称 |
TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS |
摘要 |
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed. |
申请公布号 |
CA2726844(A1) |
申请公布日期 |
2009.12.23 |
申请号 |
CA20092726844 |
申请日期 |
2009.06.19 |
申请人 |
GENENTECH, INC. |
发明人 |
ZHU, BING-YAN;SIU, MICHAEL;MAGNUSON, STEVEN R.;PASTOR, RICHARD;HAIYING, HE;YISONG, XIAO;JIFU, ZHENG;XING, XU;JUNPING, ZHAO;LIU, WENDY |
分类号 |
C07D471/04;A61K31/437;A61K31/444;A61K31/4545;A61K31/496;A61K31/5377;A61P9/00;A61P25/28;A61P29/00;A61P35/00 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|