发明名称 METHODS OF SCREENING AGENTS, CONJUGATES OR CONJUGATE MOIETIES FOR TRANSPORT BY A PEPT2 TRANSPORTER
摘要 The invention provides methods of screening agents, conjugates or conjugate moieties, linked or linkable to agents, for capacity to be transported as substrates through the PEPT2 transporter. The invention also provides methods of treatment involving delivery of agents that either alone, or as a result of linkage to a conjugate moiety, are substrates of the PEPT2 transporter. The invention also provides conjugates comprising a pharmaceutical agent which is linked to a conjugate moiety that is a substrate for a PEPT2 transporter.
申请公布号 US2009306036(A1) 申请公布日期 2009.12.10
申请号 US20090390327 申请日期 2009.02.20
申请人 XENOPORT, INC. 发明人 ZERANGUE NOA;DIAS TRACY;DOWER WILLIAM J.
分类号 A61K31/545;G01N33/50;A61K9/22;A61K38/00;A61K47/22;A61K47/42;A61K47/48;C07C237/12;C07C237/20;C07C317/50;C07C323/59;C07C323/60;C07D207/16;C07D233/54;C07K5/02;C07K5/06;C12N15/09;C12Q1/02;G01N33/15;G01N33/566 主分类号 A61K31/545
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