发明名称 DUAL-ACTING ANTIHYPERTENSIVE AGENTS
摘要 The invention relates to compounds having the formula: wherein: Q, W, Y, Z, r, and Ar are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 US2009270473(A1) 申请公布日期 2009.10.29
申请号 US20090431056 申请日期 2009.04.28
申请人 ALLEGRETTI PAUL;CHOI SEOK-KI;GENDRON ROLAND;FATHEREE PAUL R;MCKINNELL ROBERT MURRAY 发明人 ALLEGRETTI PAUL;CHOI SEOK-KI;GENDRON ROLAND;FATHEREE PAUL R.;MCKINNELL ROBERT MURRAY
分类号 A61K31/4184;A61K31/4164;A61K31/4178;A61P9/00;A61P9/12;C07D233/54;C07D235/02 主分类号 A61K31/4184
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