发明名称 ERYTHROPOIETIN SOLUTION PREPARATION USING POLYPHOSPHORIC ACID AS STABILIZER
摘要 <P>PROBLEM TO BE SOLVED: To provide a stable erythropoietin solution preparation, especially a stable feline erythropoietin solution preparation where conventionally no case of a formulated preparation is available. Ž<P>SOLUTION: This erythropoietin solution preparation containing a polyphosphoric acid as a stabilizer is effective as the erythropoietin solution preparation since it holds the activity of the erythropoietin and is stable for a long period of time. Further it is preferable that the concentration of the polyphosphoric acid is 1 μM to 1 mM, the citric acid buffer solution of pH 6.0 to 7.0 is contained, sodium chloride as an isotonifier is contained, polysorbate 80 as an adsorption inhibitor is contained and maltose as the stabilizer is further contained. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
申请公布号 JP2009249292(A) 申请公布日期 2009.10.29
申请号 JP20080094973 申请日期 2008.04.01
申请人 TORAY IND INC 发明人 IDO TAKAYOSHI;YAMADA MASANARI
分类号 A61K38/22;A61K9/08;A61K47/02;A61K47/12;A61K47/26;A61K47/34;A61P7/06 主分类号 A61K38/22
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