发明名称 |
ANTITUMOR AGENT FOR UNDIFFERENTIATED GASTRIC CANCER |
摘要 |
The present invention relates to a therapeutic agent represented by the General formula (I), or a pharmacologically acceptable salt thereof, or a solvate of the compound or the salt thereof: The therapeutic agent comprises a substance having the activity of inhibiting kinase activity of fibroblast growth factor receptor 2 ("FGFR2"). The therapeutic agent can be used for treating undifferentiated gastric cancer, and can also be used to treat organisms comprising a cell overexpressing FGFR2 or a cell expressing mutant FGFR2, or both. The present invention further relates to a pharmaceutical composition comprising an FGFR2 inhibitory and methods of treatment therewith. The present invention also relates to a method for predicting the effect of an FGFR2 inhibitory substance on a patient.
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申请公布号 |
US2009264464(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
US20070439339 |
申请日期 |
2007.08.27 |
申请人 |
EISAI R & D MANAGEMENT CO., LTD. |
发明人 |
YAMAMOTO YUJI;MATSUSHIMA TOMOHIRO;TSURUOKA AKIHIKO;OBAISHI HIROSHI;NAKAGAWA TAKAYUKI |
分类号 |
A61K31/47;C07D215/233;C12Q1/02;C12Q1/68;G01N33/567 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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