发明名称 |
ON01910.NA ENHANCES CHEMOTHERAPEUTIC AGENT ACTIVITY IN DRUG-RESISTANT TUMORS |
摘要 |
The invention includes compositions and methods of treatment of cancers susceptible to treatment with nucleotide analog chemotherapeutic agent, including cancers in which nucleotide analog resistant tumors have developed, including identifying a subject having cancer susceptible to treatment with a nucleotide analog chemotherapeutic agent and a mitotic disruptor/ polo-like kinase (PIk) pathway inhibitor to a subject; and monitoring the subject for a reduction or stabilization of at least one sign or symptom of cancer. |
申请公布号 |
CA2721722(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
CA20082721722 |
申请日期 |
2008.04.17 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
JIMENO, ANTONIO;HIDALGO, MANUEL MEDINA |
分类号 |
A61K31/425 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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