| 摘要 |
<p>The present invention is concerned with novel indol-3-yl-carbonyl-azaspiropiperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) wherein R1 to R6, U, V, W, X, Y and Z are as defined in the specification.</p> |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;BISSANTZ, CATERINA;GRUNDSCHOBER, CHRISTOPHE;MASCIADRI, RAFFAELLO;RATNI, HASANE;ROGERS-EVANS, MARK;SCHNIDER, PATRICK |
发明人 |
BISSANTZ, CATERINA;GRUNDSCHOBER, CHRISTOPHE;MASCIADRI, RAFFAELLO;RATNI, HASANE;ROGERS-EVANS, MARK;SCHNIDER, PATRICK |
